Публикации Лаборатории Химической Трансформации Антибиотиков

 

  1. Omelchuk O.A., Malyshev V.I., Medvedev M.G., Lysenkova L.N., Belov N.M., Dezhenkova L.G., Grammatikova N.E., Scherbakov A.M., Shchekotikhin A.E. Stereochemistries and Biological Properties of Oligomycin A Diels–Alder Adducts. Journal of Organic Chemistry 2021, 86, 12, 7975–7986. DOI: 10.1021/acs.joc.1c00296.

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  2. Scherbakov A.M., Sorokin D.V., Omelchuk O.A., Shchekotikhin A.E., Krasil'nikov M.A. Glucose starvation greatly enhances antiproliferative and antiestrogenic potency of oligomycin A in MCF-7 breast cancer cells. Biochimie 2021, 186, 51–58. DOI: 10.1016/j.biochi.2021.04.003.

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  3. Volodina Y.L., Tikhomirov A.S., Dezhenkova L.G., Ramonova A.A., Kononova A. V., Andreeva D. V., Kaluzhny D.N., Schols D., Moisenovich M.M., Shchekotikhin A.E., Shtil A.A. Thiophene-2-carboxamide derivatives of anthraquinone: A new potent antitumor chemotype. European Journal of Medicinal Chemistry 2021, № 221, 113521. DOI: 10.1016/j.ejmech.2021.113521.

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  4. Tikhomirov A.S., Abdelhamid M.A.S., Nadysev G.Y., Zatonsky G.V., Bykov E.E., Chueh P.J., Waller Z.A.E., Shchekotikhin A.E. Water-Soluble Heliomycin Derivatives to Target i-Motif DNA. Journal of Natural Products 2021, 84(5), 1617-1625. doi:10.1021/acs.jnatprod.1c00162.

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  5. Moiseenko E.I., Erdei R., Grammatikova N.E., Mirchink E.P., Isakova E.B., Pereverzeva E.R., Batta G., Shchekotikhin A.E. Aminoalkylamides of Eremomycin Exhibit an Improved Antibacterial Activity. Pharmaceuticals 2021, 14(4), 379. doi:10.3390/ph14040379.

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  6. Blokhina S.V., Ol'khovich M. V., Sharapova A. V., Levshin I. B., Perlovich G. L. Study of dissolution and transfer processes of new bioactive thiazolo[4,5-d]pyrimidine derivatives in modeling biological systems. Journal of Molecular Liquids 2021, 337, 116395. doi:10.1016/j.molliq.2021.116395

  7. Volkova T. V., Simonova O. R., Levshin I. B., Perlovich G.L. Physicochemical profile of new antifungal compound: pH-dependent solubility, distribution, permeability and ionization assay. Journal of Molecular Liquids 2021, 116535 doi.org/10.1016/j.molliq.2021.116535.

  8. Blokhina S. V., Sharapova A. V., Ol'khovich M. V., Doroshenko I. A., Levshin I. B., Perlovich G. L. (). Synthesis and antifungal activity of new hybrids thiazolo[4,5-d]pyrimidines with (1H-1,2,4)triazole. Bioorganic and Medicinal Chemistry Letters 2021, 40, 127944. doi.org/10.1016/j.bmcl.2021.127944

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  9. Izsépi L., Erdei R., Tevyashova A.N., Grammatikova N.E., Shchekotikhin A.E., Herczegh P., Batta G. Bacterial cell wall analogue peptides control the oligomeric states and activity of the glycopeptide antibiotic Eremomycin: solution NMR and antimicrobial studies. Pharmaceuticals 2021, 14(2), 83; https://doi.org/10.3390/ph14020083

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  10. Тевяшова А.Н., Чудинов М.В. Прогресс в медицинской химии органических соединений бора. Успехи химии 2021, 90(4), 451–487; https://doi.org/10.1070/RCR4977

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  11. Tevyashova A.N. Recent trends in synthesis of chloramphenicol new derivatives. Antibiotics 2021, 10, 370 https://doi.org/10.3390/antibiotics10040370

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  12. Litvinova V.А., Tikhomirov A.S. New methods for synthesis of 1-benzothiophene-3-carboxylic acid derivatives (microreview). Chemistry of Heterocycic Compounds 2021, 57(2), 131–133. DOI: https://doi.org/10.1007/s10593-021-02882-x.

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  13. Singh M., Malhotra L., Haque M.A., Kumar M., Tikhomirov A.S, Litvinova V. A, Korolev A.M., Ethayathulla A.S., Das U., Shchekotikhin A.E., Kaur P. Heteroarene-fused anthraquinone derivatives as potential modulators for human aurora kinase B. Biochimie 2021, 182, 152-165. DOI: https://doi.org/10.1016/j.biochi.2020.12.024

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  14. Buravchenko G.I., Scherbakov A.M., Dezhenkova L.G., Bykov E.E., Solovieva S.E., Korlukov A.A., Sorokin D.V., Monzote Fidalgo L, Shchekotikhin A.E. Discovery of derivatives of 6(7)-amino-3-phenylquinoxaline-2-carbonitrile 1,4-dioxides: novel, hypoxia-selective HIF-1α inhibitors with strong antiestrogenic potency. Bioorganic Chemistry 2020, 104, 104324, doi: 10.1016/j.bioorg.2020.104324.p1

     

  15. Monzote L., Scherbakov A.M., Scull R., Satyal P., Cos P., Shchekotikhin A.E., Gille L., Setzer W.N. Essential Oil from Melaleuca leucadendra: Antimicrobial, Antikinetoplastid, Antiproliferative and Cytotoxic Assessment. Molecules 2020, 25, 5514, doi: 10.3390/molecules25235514.p2

     

  16. Monzote L., Scherbakov A. M., Scull R., Gutierrez Y. I., Satyal P., Cos P., Shchekotikhin A. E., Gille L., Setzer W. N. Pharmacological Assessment of the Carvacrol Chemotype Essential Oil From Plectranthus amboinicus Growing in Cuba. Natural Product Communications 2020, 15, № 10, 1–12, DOI: 10. 1177/ 1934 578X 20962233.p3
  17. Моисеенко Е. И., Грамматикова Н. Э., Щекотихин А. Е. Синтез и антибактериальная активность аминоалкиламидов эремомицина. Макрогетероциклы 2020, Т. 13, № 3, 298-304, DOI: 10.6060/mhc200812s p4

     

  18. Lavrenov S.N., Isakova E.B., Panov A.A., Simonov A.Y., Tatarsky V.V., Trenin A.S. N-(Hydroxyalkyl) Derivatives of tris(1H-indol-3-yl)methylium salts as promising antibacterial agents: Synthesis and biological evaluation. Pharmaceuticals 2020, 13 (12), 469, https://doi.org/10.3390/ph13120469p5

     

  19. Bespyatykh J., Bespiatykh D., Malakhova M., Klimina K., Bespyatykh A., Varizhuk A., Tevyashova A., Nikolenko T., Pozmogova G., Ilina E., Shitikov E. Aureolic Acid Group of Agents as Potential Antituberculosis Drugs. Antibiotics 2020, 9(10), 715-730. DOI: 10.3390/antibiotics9100715p6

     

  20. D.V. Andreeva, A.S. Tikhomirov, A.E. Shchekotikhin. Ligands of G-quadruplex nucleic acids, Russian Chemical Reviews 2021, 90(1), 1-38, DOI: 10.1070/RCR4968p7

     

  21. Shchegravina E.S., Svirshchevskay E.V., Combes S., Allegro D., Barbier P., Gigant B., Varela P.F., Gavryushin A.E., Kobanova D.A., Shchekotikhin A.E., Fedorov A.Yu. Discovery of dihydrofuranoallocolchicinoids - Highly potent antimitotic agents with low acute toxicity. European Journal of Medicinal Chemistry, 2020, 207, 112724. doi: 10.1016/j.ejmech.2020.112724. 1

     

  22. Popov A., Klimovich A., Styshova O., Moskovkina T., Shchekotikhin A., Grammatikova N., Dezhenkova L., Kaluzhny D., Deriabin P., Gerasimenko A., Udovenko A., Stonik V. Design, synthesis and biomedical evaluation of mostotrin, a new water soluble tryptanthrin derivative. International Journal of Molecular Medicine, 2020, 46(4), P. 1335-1346. DOI: 10.3892/ijmm.2020.4693 2

     

  23. Litvinova V.A., Tikhomirov A.S., Ivanov I.V., Solovieva S.E., Shchekotikhin A.E. A facile access to 2-substituted naphtho[2,3-g]quinoline-3-carboxylic acid esters via intramolecular cyclization and PyBOP-promoted functionalization. Tetrahedron, 2020, 76(36), 131418. https://doi.org/10.1016/j.tet.2020.131418  3

     

  24. Andreeva D.V., Tikhomirov A.S., Dezhenkova L.G., Kaluzhny D.N., Mamaeva O.K., Solovyova S.E., Sinkevich Y.B., Shchekotikhin A.E. Heterocyclic analogs of 5,12-naphthacenequinone 16. Synthesis and properties of new DNA ligands based on 4,11-diaminoanthra[2,3-b]thiophene-5,10-dione. Chemistry of Heterocyclic Compounds, 2020, 56(6), 727–733, DOI: 10.1007/s10593-020-02723-3 

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  25. Vasin A.G., Dezhenkova L.G., Ivanov I.V., Scherbakov A.M., Shchekotikhin A.E. Synthesis and antiproliferative activity of salicylidenehydrazones based on indole-2(3)-carboxylic acids. Chemistry of Heterocyclic Compounds, 2020, 56(6), 734–740, DOI: 10.1007/s10593-020-02724-2  5

     

  26. Lavrenov S.N., Bychkova O.P., Dezhenkova L.G., Mkrtchyan A.S., Tatarskiy V.V., Tsvigun E.A., Trenin A.S. Synthesis and study of cytotoxic activity of novel 3,3-bis(indol-3-yl)-1,3-dihydroindol-2-ones. Chemistry of Heterocyclic Compounds, 2020, 56(6), Р.741–746, DOI: 10.1007/s10593-020-02725-1  6
  27. Tevyashova A.N. Oxaborine derivatives: synthesis and therapeutic potential (minireview). Chemistry of Heterocyclic Compounds, 2020, 56 (6), 715–718. https://doi.org/10.1007/s10593-020-02720-6 7

     

  28. Tevyashova A.N., Bychkova E.N., Solovieva S.E., Zatonsky G.V., Grammatikova N.E., Isakova E.B., Mirchink E.P., Treshchalin I.D., Pereverzeva E.R., Bykov E.E., Efimova S.S., Ostroumova O.S., Shchekotikhin A.E. Discovery of Amphamide, a Drug Candidate for the Second Generation of Polyene Antibiotics. ACS Infectious Diseases, 2020, 6, 2029−2044 https://dx.doi.org/10.1021/acsinfecdis.0c00068  8

     

  29. Beniaminov A.D., Chashchina G.V., Livshits M.A., Kechko O.I., Mitkevich V.A., Mamaeva O.K., Tevyashova A.N., Shtil A.A., Shchyolkina A.K., Kaluzhny D.N. Discrimination between G/C Binding Sites by Olivomycin A Is Determined by Kinetics of the Drug-DNA Interaction. International Journal of Molecular Sciences, 2020, 21(15), 5299 https://doi.org/10.3390/ijms21155299 9

     

  30. Kuliabina E.V., Tevyashova A.N., Solov’eva S.E., Melkova O.N., Guskova E.A. Reference Materials of Composition of Biologically Active Substances. Measurement Techniques, 2020, 63(4), 325-331 https://doi.org/10.1007/s11018-020-01790-4. 10

     

  31. Tikhomirov A.S., Litvinova V.A., Andreeva D.V., Tsvetkov V.B., Dezhenkova L.G., Volodina Y.L., Kaluzhny D.N.,Treshalin I.D., Schols D. Ramonova A.A., Moisenovich M.M., Shtil A.A., Shchekotikhin A.E. Amides of pyrrole- and thiophene-fused anthraquinone derivatives: A role of the heterocyclic core in antitumor properties. European Journal of Medicinal Chemistry, 2020, 199, 112294. https://doi.org/10.1016/j.ejmech.2020.112294.mm1

     

  32. Sagnou M., Novikov F.N., Ivanova E.S., Alexiou P., Stroylov V.S., Titov I.Y., Tatarskiy V.V., Vagida M. S., Pelecanou M., Shtil A.A., Chilov G.G. Novel curcumin derivatives as P-glycoprotein inhibitors: Molecular modeling, synthesis and sensitization of multidrug resistant cells to doxorubicin. European Journal of Medicinal Chemistry, 2020, 198, 112331, https://doi.org/10.1016/j.ejmech.2020.112331m2
  33. Shchekotikhin A.E., Treshalina H.M., Treshchalin M.I., Pereverzeva E.R.,Isakova H.B., Tikhomirov A.S. Experimental Evaluation of Anticancer efficiency and acute toxicity of anthrafuran for oral administration, Pharmaceuticals 2020, 13(5), 81, https://doi.org/10.3390/ph13050081mm

  34. Vatlin A.A., Bekker O.B., Lysenkova L.N., Shchekotikhin A.E., Danilenko V.N. Bioinformatics Analysis of Genes of Streptomyces Xinghaiensis (Fradiae) ATCC 19609 With a Focus on Mutations Conferring Resistance to Oligomycin A and Its Derivatives. Journal of Global Antimicrobial Resistance, 2020, 22, 47-53. doi:10.1016/j.jgar.2020.01.026.

  35. Buravchenko G.I., Scherbakov А.M., Korlukov A.А., Dorovatovskii P.V., Shchekotikhin A.E. Revision of the regioselectivity of the Beirut reaction of monosubstituted benzofuroxans with benzoylacetonitrile. 6-Substituted quinoxaline-2-carbonitrile 1,4-dioxides: structural characterization and estimation of anticancer activity and hypoxia selectivity. Current Organic Chemistry, 2020, 17, 1-11, DOI: 10.2174/1570179416666191210100754g1
  36. Ferino A., Nicoletto G., D’Este F. Zorzet S., Lago S., Richter S.N., Tikhomirov A., Shchekotikhin A., Xodo L.E. Photodynamic therapy for ras-driven cancers: targeting g-quadruplex RNA structures with bifunctional alkyl-modified porphyrins. Journal of Medicinal Chemistry, 2020, 63(3), 1245-1260. https://doi.org/10.1021/acs.jmedchem.9b01577g2
  37. Olsufyeva E.N., Yankovskaya V.S., Main trends in the design of semi-synthetic antibiotics of a new generation, Russian Chemical Reviews, 2020, 89(3), 339–378. DOI: https://doi.org/10.1070/RCR4892 g3

     

  38. A.S. Tikhomirov, I.V. Ivanov, A.M. Korolev, A.E. Shchekotikhin. β-Hydroxylation of anthraquinone derivatives with benzaldehyde oxime as a source of hydroxyl group. Tetrahedron, 2019, 75, 130623. https://doi.org/10.1016/j.tet.2019.130623
     

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  39. Panov A.A., Lavrenov S.N., Simonov A.Yu., Mirchink E.P., Isakova E.., Trenin A.S. // Synthesis and antimicrobial activity of 3,4-bis(arylthio)maleimides. /J. Antibiot (Tokyo). 2019. V. 71. № 2. P. 122-124. DOI : 10.1038/s41429-018-0122-3.
     

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  40. Tevyashova A.N., Korolev A.M., Mirchink E.P., Isakova E.B., Osterman I.A. //Synthesis and evaluation of biological activity of benzoxaborole derivatives of azithromycin. / J. Antibiot (Tokyo). 2019. V. 72. № 1. Р.22-33. DOI: 10.1038/s41429-018-0107-2
     

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  41. Tevyashova A.N., Bychkova E.N., Korolev A.M., Isakova E.B., Mirchink E.P., Osterman I.A., Erdei R., Szucs. Z., Bata G. // Synthesis and evaluation of biological activity for dual-acting antibiotics on the basis of azithromycin and glycopeptides./ Bioorganic&MedicinalChemistry Letters 2019. V. 29. № 2. P. 276-280. DOI: 10.1016/j.bmcl.2018.11.038 WOS Q2
     

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  42. Sergeev A.V., Tevyashova A.N., Vorobyov A.P., Gromova, E.S. // The Effect of Antitumor Antibiotic Olivomycin A and Its New Semi-synthetic Derivative Olivamide on the Activity of Murine DNA Methyltransferase Dnmt3a./ Biochemistry (Moscow). 2019. V. 84. № 1. P. 62-70. DOI: 10.1134/S0320972519020064

  43. Bekker O.B., Vatlin A.A., Zakharevich N.V., Lysenkova L.N., Shchekotikhin A.E., Danilenko V.N.// Draft Genome Sequence of Streptomyces xinghaiensis (fradiae) OlgR, a Strain Resistant to Oligomycin A./ Microbiol Resour Announc. 2019. V. 8. № 2. № статьи: e01531-18. DOI: 10.1128/MRA.01531-18.

  44. Моисеенко Е.И., Грамматикова Н.Э., Щекотихин А. Е.// Пиколиламиды эремомицина и катионные липогликопептиды на их основе: cинтез и оценка антимикробных свойств./ Макрогетероциклы, 2019. Т. 12. №1. С. 98-106. DOI: 10.6060/mhc181216s

  45. Ефимова C.C., Тертычная Т.Е., Лавренов С.Н., Остроумова О.С. // Механизмы действия производных трииндолилметана на липидные мембраны. /Acta Naturae. 2019. Т. 11. № 3 (42). С.38-45. DOI: 10.32607/20758251-2019-11-3-38-45

  46. Панов А. А., Лакатош С. A., Куббутат М. Х. Г., Деженкова Л. Г., Тотцке Ф., Шехтеле К. // Новые 3,4-бис(индол-1-ил)малеимиды как ингибиторы протеинкиназ. / Химия гетероциклических соединений. 2019. Т. 55. № 11. Р. 1050–1059.
     

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  47. Тевяшова А.Н., Бычкова Е.Н., Соловьева С.Е., Грамматикова Н.Э., Щекотихин А.Е.// Разработка парентеральной лекарственной формы нового противогрибкового полусинтетического полиенового антибиотика Амфамида./ Хим.-фарм. журнал. 2019. Т. 53.№10. С. 50-54.

  48. Панов А.А., Симонов А.Ю., Королёв А.М. // Синтез новых производных 3-(арилтио)малеимида./ Журнал Органической химии. 2019. Т. 55. № 12. С. 1850–1856. DOI: 10.1134/S0514749219120061
     

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  49. Lysenkova L.N., Saveljev O.Y., Omelchuk O.A., Zatonsky G.V., Korolev A.M., Grammatikova N.E., Bekker O.B., Danilenko V.N., Dezhenkova L.G., Mavletova D.A., Scherbakov A.M., Shchekotikhin A.E. Synthesis, antimicrobial and antiproliferative properties of epi-oligomycin A, the (33S)-diastereomer of oligomycin A // Natural Product Research, DOI: 10.1080/14786419.2019.1608540.
     

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  50. C.-Y. Lin, A. Islam, C.J. Su, A.S. Tikhomirov, A.E. Shchekotikhin, S.-M. Chuang, P.J. Chueh, Y.L. Chen. Engagement with tNOX (ENOX2) to Inhibit SIRT1 and Activate p53-Dependent and -Independent Apoptotic Pathways by Novel 4,11-Diaminoanthra[2,3-b]furan-5,10-diones in Hepatocellular Carcinoma Cells. Cancers 2019, 11(3), 420. doi: 10.3390/cancers11030420ga

     

  51. Y.L. Volodina, L.G. Dezhenkova, A.S. Tikhomirov, V.V. Tatarskiy, D.N. Kaluzhny, A.M. Moisenovich, M.M. Moisenovich, A.K. Isagulieva, A.A. Shtil, V.B. Tsvetkov, A.E. Shchekotikhin. New anthra[2,3-b]furancarboxamides: A role of positioning of the carboxamide moiety in antitumor properties. European Journal of Medicinal Chemistry 2019, 165, 31-45. https://doi.org/10.1016/j.ejmech.2018.12.068abstr

     

  52. Evgenia N. Olsufyeva, Andrey E. Shchekotikhin, Elena N. Bychkova, Eleonora R. Pereverzeva, Ivan D. Treshalin, Elena P. Mirchink1, Elena B. Isakova, Mikhail G. Chernobrovkin, Roman S. Kozlov, Andrey V. Dekhnich, Maria N. Preobrazhenskaya Eremomycin pyrrolidide: a novel semisynthetic glycopeptide with improved chemotherapeutic properties Drug Design, Development and Therapy 2018:12 1–11Eremomycin
  53.     G. Cozza, M. Fortuna, F. Meggio, S. Sarno, M. H. G. Kubbutat, F. Totzke,C. Schaechtele, L. A. Pinna, E. N. Olsufyeva, and M. N. Preobrazhenskaya Hydrophobic Derivatives of Glycopeptide Antibiotics as Inhibitors of Protein Kinases Biochemistry (Moscow), 2018, Vol. 83, No. 10, pp. 1222_1230. Pleiades Publishing, Ltd., 2018. Published in Russian in Biokhimiya, 2018, Vol. 83, No. 10, pp. 1523_1533.
  54.     Д. Коцца, М. Фортуна, Ф. Меггио, С. Сарно, М.Х.Д. Куббутат, Ф. Тотцк, С. Шаехтеле, Л.А. Пинна, Е.Н.Олсуфьева, М.Н. Преображенская Гидрофобные производные гликопептидных антибиотиков как новый класс ингибиторов протеинкиназ БИОХИМИЯ, 2018, том 83, вып. 10, с. 1523 – 1533 DOI: 10.1134/S032097251810007ХKotsa
  55.     Tikhomirov A.S., Tsvetkov V.B., Kaluzhny D.N., Volodina Y.L., Zatonsky G.V., Schols D., Shchekotikhin A.E. Tri-armed Ligands of G-Quadruplex on Heteroarene-fused Anthraquinone Scaffolds: Design, Synthesis and Рre-screening of Biological Properties. European Journal of Medicinal Chemistry. 2018, 159, 59-73. https://doi.org/10.1016/j.ejmech.2018.09.054.EJMC
  56.     O.A. Omelchuk, N.M. Belov, V.B. Tsvetkov, A.M. Korolev, L.G. Dezhenkova, N.E. Grammatikova, L.N. Lysenkova, O.B. Bekker, V.N. Danilenko, A.E. Shchekotikhin. Synthesis and biological activity of 16,33-O,O-diformyl-16,17-dihydro-16(S),17(R)-dihydroxyoligomycin A and 33-O-formyloligomycin A. Macroheterocycles. 2018. 11(2), 181–192. [DOI: 10.6060/mhc170834o]Mht
  57.     D.V. Andreeva, Y.B. Sinkevich, A.S. Tikhomirov, Y.N. Luzikov, A.M. Korolev, Y.B. Sinkevich, A.E. Shchekotikhin. Heterocyclic analogs of 5,12-naphtacenequinone 15. Synthesis of new anthra[2,3-b]thiophene-3(2)-carboxylic acids. Chemistry of Heterocyclic Compounds. 2018. № 6, 612-617.GR_HGS
  58. G.Y. Nadysev, A.S. Tikhomirov, L.G. Dezhenkova, A.E. Shchekotikhin, Semi-Synthetic Derivatives of Heliomycin with an Antiproliferative Potency, Recent Patents on Anti-Cancer Drug Discovery, 2018, 13.DOI:10.2174/1574892813666180723150542.
  59.    A.-C. Schulz-Fincke, A.S. Tikhomirov, A. Braune, T. Girbl, E. Gilberg, J. Bajorath, M. Blaut, S. Nourshargh, M. Gütschow. Design of an Activity-Based Probe for Human Neutrophil Elastase: Implementation of the Lossen Rearrangement To Induce Förster Resonance Energy Transfers. Biochemistry 2018, Vol. 57, 742-752.Biochem
  60.     A.S. Tikhomirov, A.A. Shtil, A.E. Shchekotikhin. Advances In the Discovery of Anthraquinone-Based Anticancer Agents. Recent Patents on Anticancer Drug Discovery 2018, 2.DOI:10.2174/1574892813666171206123114 Anticancer Drug Discovery_ 2018Anticancer_Drug_Discovery
  61.     A.S. Tikhomirov, C.-Y. Lin, Y.L. Volodina, L.G. Dezhenkova, V.V. Tatarskiy, D. A.A. Shtil, P. Kaur, P.J. Chueh, A.E. Shchekotikhin. New Antitumor Anthra[2,3-b]furan-3-carboxamides: Synthesis and Structure-Activity Relationship. European Journal of Medicinal Chemistry European Journal of Medicinal Chemistry_02_18 2018,https://doi.org/10.1016/j.ejmech.2018.02.027EJMCh
  62.     Svetlana S. Efimova, Anna N. Tevyashova, Evgenia N. Olsufyeva, Evgeny E. Bykov,Olga S. Ostroumova Pore-forming activity of new conjugate antibiotics based on amphotericin B, PLOS ONE | https://doi.org/10.1371/journal.pone.0188573 November 29, 2017, P.1-14AmphotericynB
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  64.     H.M. Treshalina, V.I. Romanenko, D.N. Kaluzhny, M.I. Treshalin, A.A. Nikitin, A.S. Tikhomirov, A.E. Shchekotikhin. Development and pharmaceutical evaluation of the anticancer Anthrafuran/Cavitron complex, a prototypic parenteral drug formulation. European Journal of Pharmaceutical Sciences. 2017. Vol. 109, 631-637. https://doi.org/10.1016/j.ejps.2017.09.025.EurJPharmSci
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  144.     Anna N Tevyashova, Nikita A Durandin, Alexander M Vinogradov, Victor B Zbarsky1,Marina I Reznikova, Lyubov G Dezhenkova, Eugeniy E Bykov, Eugenia N Olsufyeva,Vladimir A Kuzmin, Alexander A Shtil and Maria N Preobrazhenskaya. Role of the acyl groups in carbohydrate chains in cytotoxic properties of olivomycin A.The Journal of Antibiotics (2013), 1–8
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  154.     E. N. Olsufyeva, A.N. Tevyashova, I. D.Trestchalin, M. N. Preobrazhenskaya, D. Platt, and A. Klyosov . Synthesis and Antitumor Activity of New D-Galactose Containing Derivatives of Doxorubicin. Carb. Res. 338,(13), 1359- 367.(2003)
  155.     Olga V. Leontieva, Maria N. Preobrazhenskaya, and Ralph J. Bernacki. Partial circumvention of P-glycoprotein-mediated multidrug resistance by doxorubicin 14-O-hemiadipate. Investigational New Drugs, 20, 35-49 (2002)
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  158.     Alexander Y. Simonov, Evgeny E. Bykov, Sergey A. Lakatosh , Yury N. Luzikov , Alexander M. Korolev, Marina I. Reznikova, and Maria N. Preobrazhenskaya. Macrolactones built on the bis-3,4(indol-1-yl)maleimide scaffold. Tetrahedron, 2014, V. 70, Issue 3, P. 625–630 WOS. 2.772
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  161.     А.Ю.Симонов, С.А.Лакатош, Ю.Н.Лузиков, М.и.Резникова, О.Ю.Сусова, А.А.Штиль, С.М.Елизаров, В.Н.Даниленко, М.Н.Преображенская. Синтез 4-замещённых 3-[3-(диалкиламинометил)-индол-1-и]малеинимидов и изучение их способности ингибировать протеинкиназу C-α, предотвращать развитие множественной лекарственной устойчивости опухолевых клеток и цитотоксичности "Известия Академии наук. Серия химическая" 2008, 9, 1-9
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В рамках плана подготовки к сдаче кандидатского экзамена по специальности 02.00.10 "Биоорганическая химия" в Институте в течение 2008 года, ведущими специалистами нашей лаборатории Лаборатории химической трансформации антибиотиков, для наших аспирантов и соискателей был прочитан цикл лекций по ХИМИИ АНТИБИОТИКОВ. Все лекции этого цикла в виде презентаций одним архивом можно скачать ЗДЕСЬ

 

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